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Dante J Marciani, President and Chief Scientist, Qantu Therapeutics, Inc. |
Particular fucosylated glycans and glycosides, are sole anti-inflammatory immunomodulators that upon binding to the cell-surface receptor DC-SIGN, bias dendritic cells toward a tolerogenic phenotype with production of Treg cells and immunotolerance. This antigen-specific anti-inflammatory response, stimulated by vaccination, would allow the economical treatment and prevention of autoimmune diseases, without.... |