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Breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2 (ABCG2) is an ATP-binding cassette (ABC) transporter that has been implicated as a molecular cause of multidrug resistance (MDR) in a variety of cancer cells.It got its name from being cloned from a multidrug-resistant breast cancer cell line, where it was discovered to impart resistance to chemotherapeutic drugs including mitoxantrone... |
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